New vascular prosthesis to improve the quality of life of dialysis patients

Terminal renal failure is a growing medical problem and is driving an increased demand for renal replacement therapies. For the majority of patients haemodialysis is used. In this technique the blood is purified using an artificial kidney and requires access to the bloodstream via a connection between a vein and an artery, known as an arteriovenous fistula. In a significant number of cases the arteriovenous fistula fails due to thrombosis or lack of maturation, which requires the use of a vascular prosthesis for vascular access. However, the chances of developing a vascular constriction in these prostheses are high, which can result in thrombosis and blockage. By creating a new type of prosthetic material with optimum mechanical properties and blood compatibility, we will significantly reduce the risk of vascular constrictions, prolonging and improving the function of the implant and benefiting the patient’s quality of life.

Project partners

Eindhoven University of Technology, Maastricht University and University Medical Center, DSM

Patricia Dankers

Project Leader

Patricia Dankers, PhD
Eindhoven University of Technology                        

Chemelot InSciTe