The Ocular Coil Drug Delivery Comfort Trial
The administration of drugs to the eye is normally done by means of eye drops. For most patients this is easy to do, but there are disadvantages to this route of administration. For example, when applying eye drops only a proportion of the drops are retained in the eye leading to a low amount of drug being absorbed by the tissue. To counteract this, frequent administration with high drug concentrations is required, which can result in side effects or low levels of patient compliance. A new implant is being developed in the form of a flexible rod that is placed under the eyelid in the conjunctival fornix. This rod comprises a unique biomaterial that can deliver a drug over a period of weeks to months. This innovative way of drug administration results in better patient compliance with fewer side effects and improved delivery of drug to the front of the eye.
Prof. Rudy Nuijts, MD, PhD
Maastricht University Medical Center